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99% GABA
Nanjing Gemsen
CAS 56-12-2
Introduction：
Product Name | GABA |
Synonyms | Gamma-aminobutyric acid |
Appearance | White Crystals or Crystalline Powder |
CAS | 56-12-2 |
Molecular formula | C4H9NO2 |
Molecular Weight | 103.12 |
Purity | 99%min GABA |
Sample | Available |
Gamma-aminobutyric acid (GABA), also called 4-aminobutyric acid, has other common names such as aminocitric acid and piperidinic acid.
This natural substance exists widely in plants and animals, and can be found in beans, ginseng and many herbs, as well as in nerve tissues of the human brain.
GABA works as a key nerve regulator in the body, taking part in many metabolic processes and showing strong natural biological activity.
Human skin cells can produce GABA by itself, which helps keep skin stable and supports the skin’s natural repair ability.
When added to skin care products, GABA relaxes small facial muscles, boosts the production of skin elasticity fibers and collagen, repairs skin protection layer and calms sensitive skin caused by nerve stress.
When taken orally, it helps relax the body and improve sleep, which further aids skin recovery during rest at night.
With multiple beneficial functions, GABA is a practical and widely used active material for both skin care and health food products.
Specification:
Application:
1. Topical Anti-Aging & Expression Line Care
Repeated facial movements form visible expression lines around eyes, forehead and mouth.
GABA relaxes subcutaneous micro-muscles within 30–60 minutes, softening lines while keeping natural facial movement.
- Suitable for eye creams, serums, pre-event masks and daily day creams.
Recommended dosage: 0.1%–0.3%; nanoemulsion enhances skin penetration.
- High market appeal for fast visible results and easy formulation.
Dry air, temperature changes, harsh cleansers and cosmetic procedures weaken skin barrier, causing tightness, dryness and sensitivity.
GABA reduces moisture loss and accelerates stratum corneum repair, calming reactive skin quickly.
- Suitable for post-procedure creams, barrier serums and night creams. Used at 0.1%–0.3%, compatible with ceramides and hyaluronic acid.- Ideal for sensitive-skin and soothing formula lines.
Seasonal changes and environmental stress lead to dryness, dullness and loss of elasticity.
GABA boosts hyaluronic acid production and activates water-channel protein, locking long-lasting hydration for smoother, plumper skin.
- Applicable to daily moisturizers, toners, essences and sheet masks.
Recommended dosage: 0.1%–0.5%, matched with common humectants.
- High compatibility with mainstream hydrating ingredients.
Stress and irregular schedules affect relaxation and sleep.
As a natural inhibitory neurotransmitter, oral GABA eases nerve excitement, calms mood and improves sleep quality without dependency.
- Suitable for sleep gummies, chewable tablets, functional drinks and capsules.
Standard intake: 50–100 mg per serving before bedtime.
- Clean fermentation source, safe for long-term daily use.
- One single ingredient supports both beauty and health product lines.
Q&A
Q1: Is GABA safe for long-term use in skincare and oral products?
- Yes. A number of 12-month stability tests and 12-week human trials have verified its good safety profile.
No obvious adverse reactions have been recorded under recommended usage levels.
As a substance naturally existing in human body, GABA shows high skin and physical tolerance.
Q2: Can GABA be combined with other active ingredients?
- Yes. For topical use, GABA matches well with hyaluronic acid, ceramides, peptides and vitamin C derivatives.
For oral use, it is often compounded with collagen, magnesium and L-theanine.
No negative interaction has been found with common cosmetic and food raw materials.
Q3: How stable is GABA in finished products?
- GABA presents good thermal stability in formula systems. It remains stable in aqueous solution under 90°C. Nanoemulsion GABA keeps stable without obvious degradation after six-month storage at 40°C. In powder form, it can be stored for more than two years under cool and dry conditions.
Q4: Can oral and topical GABA be used together?
- Yes. The two application ways work through independent pathways. Topical GABA takes effect on facial muscles and dermal skin directly. Oral GABA regulates physical relaxation and sleep condition systematically. Combined use brings synergistic skincare effects without body burden.
Q5: Does GABA cause skin tingling or irritation?
- For most users, GABA does not bring stinging or uncomfortable feeling, with extremely low irritation risk. A small number of users may feel slight transient tingling when using high-concentration serum, which belongs to normal skin adaptation reaction. Patch test is still recommended for new formula development and product use.
Q6: How soon can consumers expect visible results?
- For improving expression lines, smoothing effect can be seen within one hour after topical application.
Long-term benefits such as improved elasticity and barrier condition need continuous use for 4 to 8 weeks.
Oral GABA may improve sleep state in a few days, while noticeable skin improvement requires several weeks of regular intake.
Q7: Is GABA suitable for vegan and clean beauty formulas?
- Yes. Fermentation-produced GABA contains no animal-derived ingredients. With good water solubility, non-toxicity and biodegradability, it fully meets the formula demands of vegan, cruelty-free and eco-friendly clean beauty lines.
Q8: What concentration of GABA is recommended for leave-on face cream?
- 0.1%–0.3% is the optimal starting concentration for daily face cream.
For targeted eye cream and intensive serum, 0.5% concentration is supported by clinical test data.
Nanoemulsion delivery can further upgrade efficacy even at lower dosage.
