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99.9%min Creatine Monohydrate
Nanjing Gemsen
CAS 6020-87-7
Introduction：
Product Name | Creatine Monohydrate |
Synonyms | Creatine Monohydrate Powder |
Appearance | White Powder |
CAS | 6020-87-7 |
Molecular formula | C4H9N3O2·H2O |
Molecular Weight | 149.19 |
Purity | 99.9%min |
Sample | Available |
Creatine monohydrate represents the scientifically foundational and most extensively validated form of creatine supplementation. Its chemical structure consists of a creatine molecule bound to a single molecule of water, forming a stable, crystalline compound. This monohydrate configuration is characterized by high purity and exceptional bioavailability. Upon ingestion, creatine monohydrate is efficiently absorbed into the bloodstream, primarily via sodium-dependent transporters, and is subsequently actively taken up by skeletal muscle tissue through a specific, saturable transport system. The primary physiological role of supplemental creatine is to augment intramuscular reserves of phosphocreatine, a critical high-energy phosphate donor.
Specification:
| Items | Standard | Method |
| Description | White Powder | crystalline powder |
| Assay | ≥99.9% | Liquid Chromatogram |
| Creatinine | ≤100ppm | Liquid Chromatogram |
| Dicyanamide | ≤20ppm | Liquid Chromatogram |
| Cyanide | ≤1ppm | Colorimetry |
| Dihydrotriazine | ≤5ppm | Colorimetry |
| Sulphate | ≤0.03% | Colorimetry |
| Test of Sulfuric Acid | No Carbonation | Visual |
| Bulk Density | ≥0.20g/ml | Measuring cylinder |
| Tap Density | ≥0.30g/ml | Measuring cylinder |
| Impurity | 1% Max | Compute |
| Heavy Metals | ≤10ppm | USP<231> |
| Lead (Pb) | ≤1ppm | USP<251> |
| Arsenic (As) | ≤1ppm | USP<211> |
| Cadmium (Cd) | ≤1ppm | USP<261> |
| Mercury (Hg) | ≤0.1ppm | USP<261> |
| Loss on Drying | ≤12.0% | USP<731> |
| Residue on Ignition | ≤0.10% | USP<281> |
| Total plate count | ≤1000cfu/g | USP<61> |
| Yeast and Molds | ≤100cfu/g | USP<61> |
| Coliforms | Negative | USP<62> |
| E Coli&Salmonella | Negative | USP<62> |
| Staphylococcus Aureus | Negative | USP<61> |
| Mesh Size | 500 mesh | Sieving |
Function and Application:
1. Creatine monohydrate supplementation effectively elevates intramuscular phosphocreatine stores, which serves to markedly accelerate the regeneration of adenosine triphosphate (ATP). This enhancement of the phosphagen energy system directly translates to improved performance in high-intensity, short-duration activities, increasing work capacity, maximal strength, and power output.
2. By facilitating greater training volume and enhancing exercise capacity, creatine monohydrate acts as a potent ergogenic aid that promotes lean tissue accretion and stimulates muscular hypertrophy, particularly of type II muscle fibers, when combined with resistance training.
3. Beyond its peripheral muscular effects, creatine monohydrate supplementation elevates cerebral phosphocreatine levels, where it functions as a crucial neuronal energy buffer. This action can support cognitive function, mitigate mental fatigue under stressful conditions, and may offer neuroprotective benefits.
4. Research indicates that creatine monohydrate can influence metabolic pathways, including improving glucose tolerance through enhanced skeletal muscle glucose transporter activity. Furthermore, it exhibits cell-stabilizing and potential anti-catabolic properties, which may aid in recovery and reduce exercise-induced muscle damage.
5. The efficacy of creatine monohydrate is well-documented across diverse populations. While beneficial for athletes, it also presents significant therapeutic potential for combating age-related sarcopenia, supporting rehabilitation, and addressing conditions characterized by creatine deficiency or increased metabolic demand.
Introduction：
Product Name | Creatine Monohydrate |
Synonyms | Creatine Monohydrate Powder |
Appearance | White Powder |
CAS | 6020-87-7 |
Molecular formula | C4H9N3O2·H2O |
Molecular Weight | 149.19 |
Purity | 99.9%min |
Sample | Available |
Creatine monohydrate represents the scientifically foundational and most extensively validated form of creatine supplementation. Its chemical structure consists of a creatine molecule bound to a single molecule of water, forming a stable, crystalline compound. This monohydrate configuration is characterized by high purity and exceptional bioavailability. Upon ingestion, creatine monohydrate is efficiently absorbed into the bloodstream, primarily via sodium-dependent transporters, and is subsequently actively taken up by skeletal muscle tissue through a specific, saturable transport system. The primary physiological role of supplemental creatine is to augment intramuscular reserves of phosphocreatine, a critical high-energy phosphate donor.
Specification:
| Items | Standard | Method |
| Description | White Powder | crystalline powder |
| Assay | ≥99.9% | Liquid Chromatogram |
| Creatinine | ≤100ppm | Liquid Chromatogram |
| Dicyanamide | ≤20ppm | Liquid Chromatogram |
| Cyanide | ≤1ppm | Colorimetry |
| Dihydrotriazine | ≤5ppm | Colorimetry |
| Sulphate | ≤0.03% | Colorimetry |
| Test of Sulfuric Acid | No Carbonation | Visual |
| Bulk Density | ≥0.20g/ml | Measuring cylinder |
| Tap Density | ≥0.30g/ml | Measuring cylinder |
| Impurity | 1% Max | Compute |
| Heavy Metals | ≤10ppm | USP<231> |
| Lead (Pb) | ≤1ppm | USP<251> |
| Arsenic (As) | ≤1ppm | USP<211> |
| Cadmium (Cd) | ≤1ppm | USP<261> |
| Mercury (Hg) | ≤0.1ppm | USP<261> |
| Loss on Drying | ≤12.0% | USP<731> |
| Residue on Ignition | ≤0.10% | USP<281> |
| Total plate count | ≤1000cfu/g | USP<61> |
| Yeast and Molds | ≤100cfu/g | USP<61> |
| Coliforms | Negative | USP<62> |
| E Coli&Salmonella | Negative | USP<62> |
| Staphylococcus Aureus | Negative | USP<61> |
| Mesh Size | 500 mesh | Sieving |
Function and Application:
1. Creatine monohydrate supplementation effectively elevates intramuscular phosphocreatine stores, which serves to markedly accelerate the regeneration of adenosine triphosphate (ATP). This enhancement of the phosphagen energy system directly translates to improved performance in high-intensity, short-duration activities, increasing work capacity, maximal strength, and power output.
2. By facilitating greater training volume and enhancing exercise capacity, creatine monohydrate acts as a potent ergogenic aid that promotes lean tissue accretion and stimulates muscular hypertrophy, particularly of type II muscle fibers, when combined with resistance training.
3. Beyond its peripheral muscular effects, creatine monohydrate supplementation elevates cerebral phosphocreatine levels, where it functions as a crucial neuronal energy buffer. This action can support cognitive function, mitigate mental fatigue under stressful conditions, and may offer neuroprotective benefits.
4. Research indicates that creatine monohydrate can influence metabolic pathways, including improving glucose tolerance through enhanced skeletal muscle glucose transporter activity. Furthermore, it exhibits cell-stabilizing and potential anti-catabolic properties, which may aid in recovery and reduce exercise-induced muscle damage.
5. The efficacy of creatine monohydrate is well-documented across diverse populations. While beneficial for athletes, it also presents significant therapeutic potential for combating age-related sarcopenia, supporting rehabilitation, and addressing conditions characterized by creatine deficiency or increased metabolic demand.