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Copper Supplement Copper Bisglycinate Copper Glycinate 10% CAS 13479-54-4

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  • Copper Bsiglycinate 10%

  • Nanjing Gemsen

  • CAS 13479-54-4

Introduction:

Product name

Copper Bisglycinate

Synonyms

Copper Glycinate

Appearance

Blue powder

CAS No.

13479-54-4

Molecular Formula C4H8CuN2O4
Purity 10%min Copper

Sample

Available


Poor bioavailability and gastric irritation, copper bisglycinate tackles both shortcomings of conventional copper. By binding copper to glycine, its chelated structure shields the mineral from stomach acid, enabling absorption through amino acid transporters and bypassing competitive mineral channels. Consequently, Bioavailability that surpasses copper sulfate or oxide, with virtually no digestive discomfort.


Copper plays an indispensable role in human physiology. It serves as a cofactor for cytochrome c oxidase, essential for cellular energy production. It activates lysyl oxidase, driving connective tissue cross-linking. And through ceruloplasmin, it enables iron mobilization. These enzymes directly influence energy levels, skin and joint integrity, and red blood cell formation.


For formulators, the advantages are clear. Higher bioavailability means lower inclusion levels still meet potency targets. Gentle tolerance expands application possibilities—from sensitive populations to clean-label products. Predictable performance streamlines development. Efficacy. Without compromise.


Specification:

Items Specifications Methods
Appearance Blue powder Visual
Copper ( (on dried basis), w/% ≥10.0 ICP - OES
Loss on drying, w/% ≤6.0 USP
PH

5.0~8.0

USP
Bulk density, g/ml ≥0.35 Balance
Tapped density, g/ml ≥0.60 Balance
Particle size, w/% 90% passing 60 mesh Sieving
Heavy metals, mg/kg ≤10 USP
Pb, mg/kg ≤1 ICP - MS
As, mg/kg ≤1 ICP - MS
Cd, mg/kg ≤1 ICP - MS
Hg, mg/kg ≤0.1 ICP - MS
Total viable count, cfu/g ≤1000 USP or GB
Yeast and mould, cfu/g ≤25 USP or GB
Coliform bacteria, /g Negative USP or GB
Escherichia coli, /g Negative USP or GB
Salmonella, /10g Negative USP or GB
Staphylococcus aureus, /g Negative USP or GB

Enterrobater sakazaki, /g

Negative USP or GB
Shigella castellani, /g Negative USP or GB


Application


1. Nutritional Supplement Formulation

Nutritional supplements aim to deliver essential minerals in forms the body can actually use. Many conventional copper sources face inherent limitations—low bioavailability, competition with other minerals for absorption, and potential for digestive upset.


Single-mineral supplements: Copper bisglycinate serves as a reliable copper source in capsules, tablets, and powder formulations targeting trace mineral replenishment.

Its predictable absorption profile allows formulators to achieve desired potency with lower inclusion levels.

Multi-vitamin and mineral blends: The chelated structure minimizes competitive interactions with zinc, iron, and other minerals, a common challenge in complex formulations.

This ensures balanced mineral delivery and simplifies formulation development.

Specialized wellness products: For formulations targeting athletes, individuals on restricted diets, or those with higher metabolic demands, copper bisglycinate provides a gentle, efficiently utilized copper source.



2. Functional Foods and Beverages

Functional foods require mineral fortifiers that withstand processing conditions, remain compatible with diverse food matrices, and deliver nutritional value without compromising taste or texture. Inorganic copper additives may react with food components, affecting both product quality and mineral availability.

Fortified Food Products: Copper bisglycinate integrates into breakfast cereals, protein bars, meal replacements, and nutritional beverages.

Its stability during processing ensures consistent copper delivery throughout shelf life without altering taste, texture, or appearance.

Processing compatibility: The chelated structure maintains integrity under moderate heat and typical pH variations encountered in food manufacturing, providing formulators with reliable, predictable performance.

Wellness-focused formulations: As consumer interest in functional foods grows, copper bisglycinate fits naturally into products positioned for energy support, skin health, or overall vitality.

Beverage Applications: The compound's excellent solubility profile supports homogeneous distribution in both ready-to-drink (RTD) beverages and powdered drink mixes.

It remains stable in liquid systems, preventing precipitation or unwanted interactions with other functional ingredients throughout the product's shelf life.


3. Pet and Animal Nutrition

Companion animals often have more sensitive digestive systems than humans. Inorganic mineral sources can lead to poor absorption, digestive disturbances, or nutrient waste—issues premium pet food manufacturers actively avoid.

Pet foods and supplements: Copper bisglycinate is incorporated into dry kibble, wet food, and nutritional supplements for dogs, cats, and other companion animals.

Its high bioavailability ensures effective copper delivery for metabolic functions including energy production, connective tissue maintenance, and healthy skin and coat.

Matrix compatibility: The ingredient blends uniformly with proteins, grains, and other nutrients without affecting palatability—a critical consideration in pet food formulation.

Life stage formulations: Suitable for products targeting puppies, kittens, adult pets, and seniors, supporting nutritional requirements across different life stages.



4. Cosmetic and Personal Care Formulations

Modern personal care products increasingly incorporate nutritional ingredients to support skin, hair, and nail health. These applications demand ingredients that are biocompatible, stable in complex formulations, and gentle enough for sensitive users.

Skin care products: Copper bisglycinate can be incorporated into moisturizers, serums, and balms, where it supports processes related to skin structure and vitality. Its chelated form reduces potential irritation, making it suitable for sensitive skin formulations.

Hair and nail care: Added to shampoos, conditioners, and treatments targeting healthy hair and nail structure, providing a nourishing mineral component.

Hypoallergenic lines: The gentle, non-irritating nature of chelated copper bisglycinate aligns with clean beauty and sensitive skin product positioning.


Q&A


Q1: What purposes does copper bisglycinate serve?
A1: It primarily addresses or prevents copper deficiency, supports energy levels, strengthens immune function, nurtures skin and hair health, and aids red blood cell production—all thanks to its high absorbability and gentle nature.



Q2: How does Copper Bisglycinate interact with other minerals, such as zinc, in a formulation?
A2: While the chelated structure reduces competition for absorptive pathways, copper and zinc still require balance. Technical data supports formulators in maintaining appropriate ratios (typically with copper at lower levels than zinc) to ensure balanced mineral status in the final product.



Q3: How can I tell if I need Copper Bisglycinate supplementation?
A3:  Blood tests measuring copper and ceruloplasmin levels, combined with symptoms like anemia, persistent fatigue, brittle hair, or skin changes, help gauge the need. Always consult a healthcare provider first.



Q4: Are there any side effects of Copper Bisglycinate?
A4: At recommended doses, side effects are uncommon. Mild digestive upset or a faint metallic taste may occur in rare cases. Excess intake, however, can trigger nausea, abdominal pain, or even liver problems—stick to dosing guidelines.



Q5: What specific benefits does Copper Bisglycinate offer in pet nutrition applications?
A5: Its high bioavailability ensures that added copper is effectively utilized by animals for essential functions like energy metabolism, connective tissue health, and coat condition. Its gentle, non-irritating nature is especially beneficial for companion animals with sensitive digestion, making it the preferred choice for premium pet formulations.



Q6: Is daily use of Copper Bisglycinate safe?
A6: For most adults, yes—when taken as recommended, it's safe and well-tolerated. Individuals with liver disease or specific genetic conditions should not use it without professional guidance.


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