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Most Popular Magnesium Supplement Magnesium Glycerophosphate CAS 927-20-8

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Quantity:
  • 98%min Magnesium Glycerophosphate

  • Nanjing Gemsen

  • CAS 927-20-8

Introduction:

Product Name

Magnesium Glycerophosphate

Appearance

White or almost white powder

CAS No.

927-20-8

Molecular formul

C₃H₇O₆PMg(C₃H₇O₆P·Mg)

Molecular weight

194.38

Purity

98%min Magnesium Glycerophosphate

Sample Available


Magnesium glycerophosphate, an organic magnesium salt produced from glycerophosphoric acid and magnesium sources, features a glycerophosphate anion that serves as a chelating carrier and supplies both magnesium and phosphorus within the same molecule. 

Magnesium participates in over 300 enzymatic reactions, yet dietary surveys indicate that a substantial proportion of the population does not meet recommended intake levels.

Although green leafy vegetables, nuts, and whole grains are magnesium-rich, soil depletion, food processing, and cooking losses compromise dietary adequacy. 

For individuals with higher physiological demands or reduced absorption capacity, supplementation becomes a practical consideration. 

Magnesium glycerophosphate combines good bioavailability with gastrointestinal tolerability, finding application across dietary supplements, functional foods, beverages, oral care, and animal nutrition.



Specification:

Items

Specifications

Method

Character

White or off white powder

EP11

Identification

Pass the test

EP11

Loss on Drying

≤ 12.0%

EP11<2.2.32>

Magnesium Content

11.0% ~ 12.5%

EP11

Heavy metal

≤10 ppm

EP11<2.4.8>

Lead (Pb)

≤ 3 ppm

EP11<2.2.23>

Cadmium (Cd)

≤ 1 ppm

EP11<2.2.23>

Mercury (Hg)

≤ 0.1 ppm

EP11

Arsenic (As)

≤ 3 ppm

EP11<2.4.8>

Chloride

≤ 0.15%

EP11<2.4.4>

Phosphates

≤ 0.5%

EP11<2.4.11>

Sulphates

≤ 0.1%

EP11<2.4.13>

Iron

≤ 150 ppm

EP11<2.4.9>

Total Plate Count

≤1000 cfu/g

EP11<2.6.12>

Total Yeast & Mold

≤100cfu/g

EP11<2.6.12>

Staphylococcus aureus

Negative

EP11<2.6.13>

Salmonella

Negative

EP11<2.6.13>

Escherichia Coli

Negative

EP11<2.6.13>

Bulk Density

≥ 0.20 g/ml

EP11

Tapped Density

≥ 0.35 g/ml

EP11

60 mesh

100%

EP11




Applications

1. Dietary Supplements

Magnesium glycerophosphate functions as a mineral source in oral supplement formats including tablets, capsules, powders, and chewable preparations. The compound delivers both magnesium and phosphorus as constituent nutrients.


  • Standard tablet and capsule formats: Direct compression grades enable streamlined manufacturing without additional granulation steps

  • Powdered blends and drink mixes: Water-soluble characteristics permit dissolution in beverages without sedimentation or cloudiness

  • Chewables and gummies: Neutral flavour profile eliminates the need for flavour-masking agents

  • Ketogenic formulations: Glycerophosphate moiety participates in both ketogenic and glucogenic metabolic pathways, relevant for specialised nutritional products

  • Tablet coatings: Functional white coating applications for tablets, capsules, and softgels


2. Functional Foods and Beverages

The ingredient is incorporated into food and beverage matrices for magnesium fortification where mineral solubility and sensory neutrality are formulation priorities.


  • Dairy-based products: Milk, yoghurt, and cheese enrichment applications

  • Beverage systems: Still and flavoured waters, soft drinks, fruit juices, and carbonated formulations

  • Sports and hydration products: Electrolyte balance modulation in beverages targeting active individuals

  • Infant and paediatric nutrition: Permitted in regulated jurisdictions for infant formula and follow-on formula applications

  • Convenience nutrition: Incorporation into snack bars, protein chews, and other ready-to-eat formats


3. Oral Care Products

Magnesium glycerophosphate functions as an oral care agent, contributing cleansing and protective effects within the oral cavity.


  • Dentifrice formulations: Toothpaste and mouthwash products where cleansing and deodorising functions are required

  • Teeth whitening products: Recognised application as a tooth-whitening agent in over-the-counter products

  • Anti-plaque preparations: Contributes to plaque inhibition in daily-use oral hygiene products


4. Animal Health and Nutrition

Magnesium glycerophosphate is incorporated into animal feed matrices as a bioavailable source of magnesium and phosphorus to support metabolic functions in production animals and companion pets.


  • Livestock and poultry nutrition: Feed fortification supporting growth performance and metabolic efficiency

  • Companion animal diets: Dietary ingredient for pet food products across dry, wet, and treat formats

  • Specialised veterinary nutrition: Formulations targeting bone development and metabolic support in young and senior animals


5. Food Contact Materials

The compound is listed in FDA regulations for use as a component in food contact substances.


  • Food packaging materials: Incorporated into materials that come into contact with food products

  • Processing equipment applications: Used in coatings or treatments for food processing surfaces

  • Paper and paperboard products: Employed in paper-based food packaging


6. Industrial and Chemical Applications

Magnesium glycerophosphate serves as a magnesium source in chemical synthesis and industrial formulations.


  • Chemical synthesis: Source of magnesium for reactions requiring soluble organic magnesium salts

  • Personal care products: Non-oral cosmetic applications where magnesium glycerophosphate provides mineral content

  • Flame retardant formulations: Emerging applications in polymer systems requiring halogen-free flame retardancy

  • Stabiliser and catalyst applications: Process aid functions in various manufacturing contexts



Frequently Asked Questions (Q&A)


Q1: What are the specified limits for magnesium content?

Pharmacopoeial specification (BP/Ph. Eur.) requires magnesium content between 11.0% and 12.5% on a dried basis. Commercial food-grade products with approximately 10.5% magnesium are also available.


Q2: What is the aqueous solubility profile?

Solubility in water at 20°C varies by product grade: some variants exceed 100 g/L, others fall within the 10–100 g/L range, and certain grades are below 1 g/L. The 1% aqueous solution pH ranges from 7.0 to 8.5.


Q3: Which pharmacopoeial monographs are applicable?

The compound is monographed in the British Pharmacopoeia (BP 2025), European Pharmacopoeia (Ph. Eur. 11.6 update), and Korean Pharmacopoeia (KP).


Q4: What is the recommended storage period and conditions?

Storage: kept well closed, dry, and at room temperature. Retest period: 36 months for all commercial grades.


Q5: How does the material behave with other formulation components??

Neutral taste and odour profile permits incorporation into complex formulations without sensory interference. The glycerophosphate moiety is reported to be compatible with probiotic strains such as Lactobacillus rhamnosus.


Q6: Is there any interaction with concurrently administered substances?

Separation from certain oral medications (tetracyclines, quinolones, nitrofurantoin, iron preparations, bisphosphonates, and penicillamine) is generally advised. A 2–4 hour interval between administrations is recommended to minimise absorption interference.


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