 |
| Quantity: | |
|---|---|
99%min L-Citrulline DL‑Malate
Nanjing Gemsen
CAS 60259-81-6
Introduction：
Product Name | L‑Citrulline DL‑Malate |
Type | 2:1; 1:1 |
Appearance | White Powder |
CAS | 60259-81-6 |
Molecular formula | C16H32N6O11 |
Purity | 99%min L-Citrulline DL‑Malate |
Sample | Available |
L‑Citrulline DL‑Malate is a compound formed from the amino acid L‑citrulline and malic acid, typically supplied in 1:1 or 2:1 molar ratios, with the 2:1 formulation being more commonly used in research. L‑citrulline serves as a direct precursor to L‑arginine, thereby supporting endogenous nitric oxide production — a key regulator of blood vessel dilation and tissue perfusion. Malic acid, a tricarboxylic acid cycle intermediate, contributes to mitochondrial ATP generation, linking amino acid metabolism with cellular energy turnover. The combination facilitates ammonia clearance via the urea cycle and enhances oxygen and nutrient delivery to active muscles, which are the primary rationales for its use in exercise and recovery contexts. Manufactured through fermentation‑based processes, the compound is available as a neutral‑tasting, highly soluble powder suitable for blending into beverages or supplement stacks. All production batches are tested for purity and ratio compliance, ensuring consistent quality for sports nutrition applications.
Specification:
| Items | Standard | Analysis Results |
| Characters | White powder | White powder |
| Identification | In accordance with standard retention time | conforms |
Optical rotation[α]D20℃ | +16.5～+18.5 | +17.3 |
| Solubility | Clear | Clear |
| Residue on ignition (%) | ≤0.1 | 0.01 |
| Moisture (%) | ≤0.5 | 0.01 |
| Chloride (%) | ≤0.02 | ＜0.02 |
| Sulfate (%) | ≤0.02 | ＜0.02 |
| Ammonium (%) | ≤0.02 | ＜0.02 |
| Arsenic (ppm) | ≤1 | ＜1 |
| Iron (ppm) | ≤30 | ＜30 |
| Heavy Metals (ppm) | ≤10 | ＜10 |
| Assay (%) | ≥99.0 | 99.64 |
| L-Citrulline（%） | 62.5～74.5 | 64.90 |
| DL-Malate（%） | 25.5～37.5 | 34.74 |
| Total Plate counts (cfu/g) | ≤1000 | ＜1000 |
| Yeast and Moulds (cfu/g) | ≤100 | ＜100 |
| E.Coli (cfu/g) | Absence | Conform |
| Salmonella (cfu/25g) | Absence | Conform |
| Staphylococcus (cfu/25g) | Absence | Conform |
Application:
For resistance training, high‑intensity interval sessions, or endurance exercise, the compound is typically taken 30 to 60 minutes before activity.
In this window, it supports blood flow to working muscles and enhances oxygen and nutrient delivery. The malate component feeds into the Krebs cycle, helping to power sustained muscular contractions.
A common single serving falls in the range of 6,000–8,000 mg of the 2:1 formulation.
During extended sessions with multiple sets, high repetitions, or repeated maximal efforts, maintaining output across work bouts becomes a key challenge.
L‑Citrulline DL‑Malate supports ammonia clearance — a byproduct that accumulates during intense protein metabolism — while malate continues to contribute to ATP regeneration.
This combination helps sustain intensity and delays the typical decline in performance observed toward the end of demanding workouts.
After training, particularly following resistance exercise or eccentric loading, recovery between sessions is a priority.
Improved circulation supports the delivery of nutrients to fatigued muscles and aids in the removal of metabolic waste.
Users often take the compound immediately after training — either in addition to pre‑workout use or as a standalone dose — to promote faster return to baseline performance and reduce perceived muscle soreness.
On non‑training days, some users maintain consistent intake with smaller, divided doses throughout the day.
This approach supports continuous circulatory function and nitrogen metabolism without targeting the acute effects needed for training sessions.
The powder form also offers excellent solubility and a neutral taste profile, making it an ideal ingredient for pre‑workout blends, intra‑workout drinks, and comprehensive amino acid formulations.
It integrates easily with other supplements without altering overall flavor.
Q&A:
Q1: What is the difference between the 1:1 and 2:1 ratios?
The numbers indicate the molar ratio of L‑citrulline to malic acid. The 2:1 ratio delivers more L‑citrulline per gram of powder, while the 1:1 version provides proportionally more malate for energy metabolism support. Research studies more frequently employ the 2:1 ratio. The choice depends on the intended application and personal preferences regarding taste, solubility, and the relative emphasis on citrulline versus malate content.
Q2: How should L‑Citrulline DL‑Malate be taken?
For training days, take 6,000–8,000 mg of the 2:1 formulation approximately one hour before exercise. On rest days, the same total daily amount can be divided into smaller doses taken throughout the day. The powder mixes easily with water, juice, or other beverages. Always follow the specific serving recommendations on the product label.
Q3: Is this the same as pure L‑citrulline?
Not exactly. L‑Citrulline DL‑Malate combines L‑citrulline with malic acid to form a stable compound. While pure L‑citrulline provides the amino acid component, the addition of malate offers extra support for energy production through the Krebs cycle. The compound form also tends to provide better stability and solubility than L‑citrulline alone.
Q4: Are there any side effects?
L‑Citrulline DL‑Malate is considered safe for use in dietary supplements. Some individuals report mild gastrointestinal discomfort, particularly at higher doses. As with any supplement, responses vary from person to person. Starting with a lower amount to assess personal tolerance is always a sensible approach.
Q5: Can it be combined with other supplements?
Yes. The unflavored powder blends seamlessly with protein shakes, pre‑workout stacks, intra‑workout drinks, or simply water. Its compatibility with a wide range of dietary products makes it a versatile addition to various supplementation protocols.
Q6: How soon are effects noticeable?
Acute effects — such as those related to same‑session performance — may be experienced when the compound is taken about one hour before training. For recovery benefits and overall training adaptation, consistent use over several days to weeks is more relevant. Individual responses vary, and results depend on factors such as training volume, diet, and baseline fitness levels.
