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China Manufacturer 95% Hesperidin Citrus Aurantium Extract CAS 520-26-3

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Quantity:
  • 95% Hesperidin

  • Nanjing Gemsen

  • 520-26-3

Introduction:

Product Name

Hesperidin

Synonym

Citrus Aurantium Extract

Appearance

Brown to light yellow

CAS

520-26-3

Molecular Formula

C28H34O15

Molecular Weight  

610.56

Purity 

80%-95%min Hesperedin

Sample

Available


Hesperidin, a natural substance found in citrus fruits, remains stable at room temperature but easily degrades when exposed to strong oxidizing agents. Primarily sourced from the peels and white inner layers of oranges, lemons, and other citrus fruits, it can also be found in plants like mint. As a safe and effective natural ingredient, it is widely used in food, cosmetics, and health products.


Specification:

Items Specifications Results Method
Color

Brown to light yellow

Conform Organoleptic
Odour Characteristic Conform Organoleptic
Appearance Fine powder Conform Organoleptic
Identification Identical to RS. sample Identical HPTLC
Hesperedin >95.0% 95.31% HPLC (on anhydrous basis)
Sieve analysis 100% through 80 mesh Conform Eur. Ph. <2.9.12>
Water(KF) ≤5.0% 3.41% Eur. Ph. <2.5.12>
Total Ash ≤1.0% 0.61% Eur, Ph. <2.4.16>
Bulk density 40-60 g/100ml 54 g/100ml Eur. Ph. <2.9.34>
Tap density 60-90 g/100ml 67 g/100ml Eur. Ph. <2.9.34>
Lead (Pb) ≤3.0 mg/kg 0.0846 mg/kg Eur. Ph. <2.2.58>ICP-MS
Arsenic (As) ≤2.0 mg/kg 0.0814 mg/kg Eur. Ph. <2.2.58>ICP-MS
Cadmium (Cd) ≤1.0 mg/kg <0.01 mg/kg Eur. Ph. <2.2.58>ICP-MS
Mercury (Hg) ≤ 0.1 mg/kg 0.0149 mgkg Eur. Ph. <2.2.58>ICP-MS
Solvents Residue Meet Eur. Ph. <2.4.24> Conform Eur. Ph. <2.4.24>
Pesticides Residue Meet Eur. Ph. <2.8.13> Conform Eur. Ph. <2.8.13>
Total Plate Count ≤10000 cfu/g 80 cfu/g Eur. Ph. <2.6.12>
Yeast & Mold ≤1000 cfu/g 90 cfu/g Eur. Ph. <2.6.12>
E.Coli Negative Conform Eur. Ph. <2.6.13>
Salmonella Negative Conform Eur. Ph. <2.6.13>
Non-Irradiation ≤700
299 EN <13751:2002>
Packing&Storage

Packed in paper-drums and two plastic-bags inside.

Store in a well-closed container Away from moisture,light, oxygen

Shelf life 36 months under the conditions above and in its original packaging


Application


1. Healthcare Products

Hesperidin, a natural plant ingredient proven safe for human use, easily fits into health products. Its properties make it ideal for supplements, mixing smoothly with natural partners like vitamin C.

Common applications include:

·Simple capsules and tablets for daily plant-based health support.

·Blood health supplements combined with plant extracts for better results.

·Daily health products enriched with vitamins and plant extracts for richer nutrition.


2. Food Industry

Hesperidin, a natural plant antioxidant, fights oxidation to keep food fresh longer. It replaces or works with synthetic additives, matching today’s demand for natural ingredients. As a plant-based booster, it adds extra nutrition to foods.

Common uses:

·Added to oils, pastries, and meats to prevent spoilage and make products last longer.

·Mixed into fruit juices and health powders to boost plant-based nutrients.

·Blended with yogurt and milk drinks for better nutrition.


3. Cosmetic Industry

Hesperidin, a natural plant antioxidant, fights skin damage from free radicals and UV rays. It works with sunscreens to boost protection, fitting perfectly in gentle, natural skincare.

Common uses:

·Added to serums, creams, and toners to strengthen antioxidant power and keep skin healthy.

·Mixed into sunscreens alongside physical or chemical filters for stronger UV defense.

·Used in sensitive-skin products as a soothing ingredient to reduce irritation and improve results.


4. Pharmaceutical Auxiliaries

Hesperidin can be turned into hesperetin, a key building block used to create specialty chemicals and medicine parts. As a natural plant compound, it’s widely used in drug development. Its stability makes it reliable for medicine production.

Common uses:

·Used to make hesperetin for sweeteners and specialty chemicals.

·Used in medicine making as a pure powder for drug formulas.

·Used in lab tests as a benchmark for measuring plant flavonoids.


Q&A


Q1: What is the recommended storage condition for hesperidin?

A1: Store solid hesperidin powder refrigerated (2–8°C) for short-term use. For long-term storage, keep it sealed at -20°C to extend shelf life up to 3 years. Prepared hesperidin solutions should be stored at -80°C and used promptly to avoid repeated freezing and thawing. If stored at -20°C, the shelf life is approximately 1 year. All forms must be kept away from strong oxidizing agents and direct sunlight.


Q2: Is hesperidin soluble in water? What solvents are suitable for its dissolution?

A2: Hesperidin is insoluble in water and alcohol (ethanol), a key physicochemical trait. It dissolves well in organic solvents like pyridine and dimethylformamide (DMF). In experiments or industrial applications, dimethyl sulfoxide (DMSO) is commonly used. With ultrasonic assistance, its solubility in DMSO can reach 100 mg/mL, ideal for preparing concentrated stock solutions.



Q3: Do different hesperidin purities (e.g., 95% and others) correspond to different functions?

A3: Hesperidin’s core functions—antioxidant, compatibility, stability—are determined by its structure, not purity. Purity mainly affects usage scenarios and dosage needs:

·High purity (≥95%): Used in pharmaceuticals, premium supplements, and lab standards. Requires minimal impurities to ensure safety and consistent effects.

·Medium-low purity (50%–90%): For food additives and general cosmetics. Balances cost and effectiveness, meeting basic antioxidant needs without strict purity limits.

·Key note: Higher purity ≠ stronger effect, but needs less dosage to work. Lower purity may require more usage and is unsuitable for applications with strict impurity limits (e.g., drug production).


Q4: Can hesperidin be used in combination with other active ingredients? What are the common combination forms?

A4: Hesperidin works well with various natural ingredients and nutrients.

Common combinations include:

·Vitamin C – Boost antioxidant effects.

·Diosmin – Used in daily health supplements for compound formulas.

·Grape seed extract, green tea extract – Broaden active ingredient diversity, enhancing overall product benefits.

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