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95% Hesperidin
Nanjing Gemsen
520-26-3
Introduction:
Product Name | Hesperidin |
Synonym | Citrus Aurantium Extract |
Appearance | Brown to light yellow |
CAS | 520-26-3 |
Molecular Formula | C28H34O15 |
Molecular Weight | 610.56 |
Purity | 80%-95%min Hesperedin |
| Sample | Available |
Hesperidin, a natural substance found in citrus fruits, remains stable at room temperature but easily degrades when exposed to strong oxidizing agents. Primarily sourced from the peels and white inner layers of oranges, lemons, and other citrus fruits, it can also be found in plants like mint. As a safe and effective natural ingredient, it is widely used in food, cosmetics, and health products.
Specification:
| Items | Specifications | Results | Method |
| Color | Brown to light yellow | Conform | Organoleptic |
| Odour | Characteristic | Conform | Organoleptic |
| Appearance | Fine powder | Conform | Organoleptic |
| Identification | Identical to RS. sample | Identical | HPTLC |
| Hesperedin | >95.0% | 95.31% | HPLC (on anhydrous basis) |
| Sieve analysis | 100% through 80 mesh | Conform | Eur. Ph. <2.9.12> |
| Water(KF) | ≤5.0% | 3.41% | Eur. Ph. <2.5.12> |
| Total Ash | ≤1.0% | 0.61% | Eur, Ph. <2.4.16> |
| Bulk density | 40-60 g/100ml | 54 g/100ml | Eur. Ph. <2.9.34> |
| Tap density | 60-90 g/100ml | 67 g/100ml | Eur. Ph. <2.9.34> |
| Lead (Pb) | ≤3.0 mg/kg | 0.0846 mg/kg | Eur. Ph. <2.2.58>ICP-MS |
| Arsenic (As) | ≤2.0 mg/kg | 0.0814 mg/kg | Eur. Ph. <2.2.58>ICP-MS |
| Cadmium (Cd) | ≤1.0 mg/kg | <0.01 mg/kg | Eur. Ph. <2.2.58>ICP-MS |
| Mercury (Hg) | ≤ 0.1 mg/kg | 0.0149 mgkg | Eur. Ph. <2.2.58>ICP-MS |
| Solvents Residue | Meet Eur. Ph. <2.4.24> | Conform | Eur. Ph. <2.4.24> |
| Pesticides Residue | Meet Eur. Ph. <2.8.13> | Conform | Eur. Ph. <2.8.13> |
| Total Plate Count | ≤10000 cfu/g | 80 cfu/g | Eur. Ph. <2.6.12> |
| Yeast & Mold | ≤1000 cfu/g | 90 cfu/g | Eur. Ph. <2.6.12> |
| E.Coli | Negative | Conform | Eur. Ph. <2.6.13> |
| Salmonella | Negative | Conform | Eur. Ph. <2.6.13> |
| Non-Irradiation | ≤700 | 299 | EN <13751:2002> |
| Packing&Storage | Packed in paper-drums and two plastic-bags inside. Store in a well-closed container Away from moisture,light, oxygen | ||
| Shelf life | 36 months under the conditions above and in its original packaging | ||
1. Healthcare Products
Hesperidin, a natural plant ingredient proven safe for human use, easily fits into health products. Its properties make it ideal for supplements, mixing smoothly with natural partners like vitamin C.
Common applications include:
·Simple capsules and tablets for daily plant-based health support.
·Blood health supplements combined with plant extracts for better results.
·Daily health products enriched with vitamins and plant extracts for richer nutrition.
2. Food Industry
Hesperidin, a natural plant antioxidant, fights oxidation to keep food fresh longer. It replaces or works with synthetic additives, matching today’s demand for natural ingredients. As a plant-based booster, it adds extra nutrition to foods.
Common uses:
·Added to oils, pastries, and meats to prevent spoilage and make products last longer.
·Mixed into fruit juices and health powders to boost plant-based nutrients.
·Blended with yogurt and milk drinks for better nutrition.
3. Cosmetic Industry
Hesperidin, a natural plant antioxidant, fights skin damage from free radicals and UV rays. It works with sunscreens to boost protection, fitting perfectly in gentle, natural skincare.
Common uses:
·Added to serums, creams, and toners to strengthen antioxidant power and keep skin healthy.
·Mixed into sunscreens alongside physical or chemical filters for stronger UV defense.
·Used in sensitive-skin products as a soothing ingredient to reduce irritation and improve results.
4. Pharmaceutical Auxiliaries
Hesperidin can be turned into hesperetin, a key building block used to create specialty chemicals and medicine parts. As a natural plant compound, it’s widely used in drug development. Its stability makes it reliable for medicine production.
Common uses:
·Used to make hesperetin for sweeteners and specialty chemicals.
·Used in medicine making as a pure powder for drug formulas.
·Used in lab tests as a benchmark for measuring plant flavonoids.
Q1: What is the recommended storage condition for hesperidin?
A1: Store solid hesperidin powder refrigerated (2–8°C) for short-term use. For long-term storage, keep it sealed at -20°C to extend shelf life up to 3 years. Prepared hesperidin solutions should be stored at -80°C and used promptly to avoid repeated freezing and thawing. If stored at -20°C, the shelf life is approximately 1 year. All forms must be kept away from strong oxidizing agents and direct sunlight.
Q2: Is hesperidin soluble in water? What solvents are suitable for its dissolution?
A2: Hesperidin is insoluble in water and alcohol (ethanol), a key physicochemical trait. It dissolves well in organic solvents like pyridine and dimethylformamide (DMF). In experiments or industrial applications, dimethyl sulfoxide (DMSO) is commonly used. With ultrasonic assistance, its solubility in DMSO can reach 100 mg/mL, ideal for preparing concentrated stock solutions.
Q3: Do different hesperidin purities (e.g., 95% and others) correspond to different functions?
A3: Hesperidin’s core functions—antioxidant, compatibility, stability—are determined by its structure, not purity. Purity mainly affects usage scenarios and dosage needs:
·High purity (≥95%): Used in pharmaceuticals, premium supplements, and lab standards. Requires minimal impurities to ensure safety and consistent effects.
·Medium-low purity (50%–90%): For food additives and general cosmetics. Balances cost and effectiveness, meeting basic antioxidant needs without strict purity limits.
·Key note: Higher purity ≠ stronger effect, but needs less dosage to work. Lower purity may require more usage and is unsuitable for applications with strict impurity limits (e.g., drug production).
Q4: Can hesperidin be used in combination with other active ingredients? What are the common combination forms?
A4: Hesperidin works well with various natural ingredients and nutrients.
Common combinations include:
·Vitamin C – Boost antioxidant effects.
·Diosmin – Used in daily health supplements for compound formulas.
·Grape seed extract, green tea extract – Broaden active ingredient diversity, enhancing overall product benefits.